Demichelis Lab - Computational Oncology

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Francesca Demichelis, PhD, Assistant Professor
CIBIO, University of Trento, Trento, Italy
ICB, Weill Cornell Medical College, New York

Address: Centre for Integrative Biology
University of Trento
Via Sommarive 14,
38123 Povo, Trento, Italy
Email: demichelis[at]science.unitn.it;
Phone: +39 0461 285305; Fax: +39 0461 283937

Short CV: F Demichelis received her PhD in February 2005 from the International PhD School on Information and Communication Technology in Trento (Italy) where she developed systematic approaches to processing and understanding data generated through Tissue Microarray Technology (modelling heterogeneity/uncertainty in classification approaches relevant to biological entities such as intra-tumor protein expression). Between 2005-2007 she worked at the Brigham and Women's Hospital (Harvard Medical School), as computational biology Post-doc fellow. In joint projects with members of research groups at the Dana Farber Cancer Institute and the Broad Institute of MIT and Harvard, she developed analytical approaches for the analysis of cancer genomics datasets related to prostate cancer disease progression as part of a multi-institutional effort. Between 2008-20011, she worked at Weill Cornell Medical College as Assistant Professor in Pathology and Laboratory Medicine and at the Institute for Computational Biomedicine. Her group focused on the study of structural variants (copy number variations - CNVs) as risk factors for cancer development and as potential facilitators (“triggers”) for specific somatic alterations (funded by DOD Young Investigator Award). From 2008 to 2010, she served as co-chair of the analysis team for Copy Number Variations in genome-wide association studies MicroArray Quality Control (MAQC) Project II, managed by FDA and was leader of the bioinformatics effort for the prostate cancer research group at Weill Cornell Medical College. In 2011 she joined the Centre for Integrative Biology at the University of Trento, Italy, where she is group leader (Computational Oncology Laboratory) and maintains Adjunct position at the Institute for Computational Biomedicine at Weill Cornell Medical College.

Activities: Grant reviewer for NCI Special Emphasis Review Panel 2009/10 ZRG1 OTC-K (58) R; NCI Special Emphasis Review Panel 2009/10 ZRG1 BDA-A (58) R; National Medical Research Council, Ministry of Health, Singapore (2010); Austrian Science Fund (FWF), Austria (2010); Ministry of Health, Italy (2010); Cancer Research UK (2011).
Reviewer for: PNAS, Genome Research, Cancer Research, Clinical Cancer Research, American Journal of Pathology, Journal of Molecular Diagnostics, International Journal of Cancer, BJ Cancer, BJU International, Bioinformatics, BMC Bioinformatics, BMC Genomics, BMC Cancer, Biostatistics, Artificial Intelligence in Medicine, Computers in Biology and Medicine.
Editorial Board of Diagnostic Pathology; Associate Editor for BMC Medical Genomics.

Funding: Current (2012) funding sources include: Department of Defense (USA), NIH, Prostate Cancer Foundation (PCF), Fondazione Trentina per la Ricerca sui Tumori.